MODIFICATION OF ULTRAVIOLET-INDUCED MUTATION FREQUENCY IN NEUROSPORA CRASSA
نویسندگان
چکیده
منابع مشابه
Ultraviolet-sensitive mutants in Neurospora crassa.
ADIATION-SENSITIVE mutants in bacteria have been reported repeatedly in recent years (s,ee SETLOW 1966). Several loci concerned with sensitivity have been mapped. Some of these mutants not only lacked the ability to repair damaged DNA but also failed to undergo genetic recombination (CLARK and MARGULIES 1965; HOWARD-FLANDERS and THERIOT 1966; VAN DE PUTTE et al. 1966). Among the eucaryotic orga...
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Duplicate DNA sequences in the genome of Neurospora crassa can be detected and mutated in the sexual phase of the life cycle by a process termed RIP (repeat-induced point mutation). RIP occurs in the haploid nuclei of fertilized, premeiotic cells before fusion of the parental nuclei. Both copies of duplications of gene-sized sequences are affected in the first generation at frequencies of appro...
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The ability of Neurospora crassa FGSC 4335 in the biotransformation of hydrocortisone was investigated. The microorganism produced two major metabolites after incubation with the substrate for seven days. Each microbial product was purified chromatographically and identified on the basis of spectral data. The products were identified as 11?,17?,20?,21-tetrahydroxypregn-4-en-3-one (II) and 11?-h...
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Forty-eight new mutations at the am locus of Neurospora crassa have been characterized. Nineteen mutations were induced by UV; of these, eight were missense, two were frameshifts, two were nonsense, three were deletions and four were unidentified. Twenty-nine mutations were induced with nitrous acid; of these, twenty-one were missense, three were frameshifts, one was nonsense, two were deletion...
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The sulfur regulatory circuit of the filamentous fungus, Neurospora crassa, consists of a set of unlinked structural genes which encode sulfur catabolic and two major regulatory genes which govern their expression. The cys-3 regulatory gene encode a transacting regulatory protein which activates the expression of cys-14 and ars, whereas the other regulatory genes Scon-l and Scon-2 appear to...
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ژورنال
عنوان ژورنال: Genetics
سال: 1961
ISSN: 1943-2631
DOI: 10.1093/genetics/46.3.247